Medical Grade Plla Polymer Poly L-Lactic Acid Raw Material for Injection Dermal Filler 3D Printing

• Customization: Available
• CAS No.: 33135-50-1
• Formula: (C6h8o4)N
• Model NO.: PLLA
• Color: White
• Material: Poly-L-Lactic Acid
• Shelf Life: 2 Years
• Purity: 99%
• MOQ: 100g
• Service: OEM/ODM
• Transport Package: 100g/Bag
• Specification: 0.3-3.0
• Trademark: Rimless
• Origin: China
• HS Code: 3907700000
• Production Capacity: 1000grams/Month

Product Description

Product Description

Differences in the application of PLLA with different intrinsic viscosities

Cosmetic and Dermatology Applications: Although PLLA is primarily used in medical settings, its derivatives or specially formulated products with controlled intrinsic viscosity can be designed for aesthetic applications like dermal fillers. Lower viscosity PLLA may be preferred for superficial treatments requiring a smoother injection and faster initial effect, whereas higher viscosity formulations can be used for deeper tissue augmentation or longer-lasting volume restoration.

Tissue Regeneration and Scaffold Design: In tissue engineering, the porosity, pore size, and interconnectivity of PLLA scaffolds play critical roles in guiding cellular infiltration and tissue formation. Lower intrinsic viscosity PLLA can produce scaffolds with larger pores and higher porosity, facilitating cell migration and nutrient exchange, which is beneficial for rapid tissue ingrowth in applications like wound healing or skin regeneration. Conversely, higher intrinsic viscosity PLLA forms denser structures, suitable for load-bearing applications like bone regeneration, where mechanical stability is paramount.
 

Injectable Biomaterials and Nanoparticles: The rheological properties of PLLA, influenced by its intrinsic viscosity, determine its injectability and suitability for forming stable suspensions or emulsions. Lower viscosity PLLA solutions or dispersions can be more easily administered via injection, making them ideal for localized drug delivery or minimally invasive cosmetic procedures. For the creation of nano- or micro-particles for drug encapsulation, controlling viscosity is essential for achieving uniform particle size and distribution, affecting drug release kinetics.
 

Compatibility with Other Polymers and Composites: PLLA is often combined with other polymers or bioactive components to enhance its properties or introduce new functionalities. Varying the intrinsic viscosity can impact the compatibility and miscibility of PLLA with these additives, influencing the blend's overall performance. For instance, a carefully selected combination of PLLA with different intrinsic viscosities can be used to create gradient structures, mimicking natural tissue interfaces or optimizing mechanical strength and degradation profiles.

Cosmeceutical Formulations: In the realm of cosmeceuticals, PLLA derivatives or low intrinsic viscosity PLLA can be incorporated into topical creams, serums, or masks, leveraging its collagen-stimulating properties for anti-aging and skin rejuvenation benefits. The lower viscosity allows for better penetration into the skin's superficial layers, promoting hydration, improving skin texture, and reducing the appearance of fine lines without the need for invasive procedures.

Product Parameters

 

Description	PLLA is a biodegradable thermoplastic aliphatic polyester, it can be completely degraded in the body. The product is excreted by metabolism and it does not have harm and side effects on the human body. Therefore our products are currently widely used in the field of medical devices, such as absorbable sutures, tissue engineering scaffolds, orthopedics, skin filling; microspheres, nanoparticles for drug delivery, etc.
Physical-chemical properties	Molecular formula            (C6H8O4)n Chemical name              Poly(L-lactide), Poly(L-lactic acid), L-polylactide CAS Registry number          33135-50-1 Chemical structure
Parameter	Item	Test Method		Specification
	Appearance	Visual		White, pale yellow powder
	Inherent Viscosity	Ubbelohde Viscometer		0.30-3.50 dl/g
	Residual Solvent	Gas Chromatography		≤0.5%
	Heavy Metal Sulfated Ash	Chemical Reagent Sulfuric Acid		≤10 ppm ≤0.1%
	For each batch a certificate of analysis is provided, showing the analytical data determined in our quality control laboratory. Additional analytical data can be made upon request.
Packaging	100g/500g/1Kg per aluminum foil bag
Recommend storage	Stored in a cool and dry place without sunlight, a refrigerator is recommended. Temperatures (2-8°C)
Shelf life	When stored in the original packaging at low temperatures (2-8°C), PLLA keeps its initial properties for at least two years.
Product catalogue	Model		IV Range dl/g		Mw Range (ten thousand)
	PL-05		0.30-0.75		1.2-4.5
	PL-10		0.75-1.25		4.5-9.5
	PL-15		1.25-1.75		9.5-19.5
	PL-20		1.75-2.25		19.5-28.5
	PL-25		2.25-2.75		28.5-40.5

Packaging & Shipping

 

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